Charged residues are major determinants of the transmembrane orient...
... signal but rather by the hydrophilic sequences flanking it. To study the role of charged residues in ... charged amino acids flanking the hydrophobic signal were mutated to residues of opposite charge, half the ... hydrophilic sequences flanking it. To study the role of charged residues in determining the membrane topology ... cytoplasmic amino terminus, was analyzed in transfected COS-7 cells. When the charged amino acids flanking the ...
Escape from a dominant HLA-B*15-restricted CD8+ T cell response aga...
... . Interestingly, mutations were also selected in the epitope flanking region, suggesting that compensatory ... epitope flanking region (S2439T and K2440Q). Functional analysis with the subgenomic replicon Con1 ... multicenter cohort in the present study. Interestingly, mutations were also selected in the epitope flanking ... (H2454R and M2456L) and substitutions in the epitope flanking region (S2439T and K2440Q). Functional ...
Precise breakpoint localization of large genomic deletions using Pa...
... , special attention must be dedicated to identical sequences flanking the breakpoints, such as poly(N ... attention must be dedicated to identical sequences flanking the breakpoints, such as poly(N) motifs. 8 ... ; however, special attention must be dedicated to identical sequences flanking the breakpoints, such as poly ... , special attention must be dedicated to identical sequences flanking the breakpoints, such as poly(N ...
Allelic configuration and polysomic inheritance of highly variable ...
... . Sequence data of 150 microsatellite alleles and their flanking regions revealed high variation, which may ... of mutation (indels and substitutions) in microsatellite flanking-sequences was a prerequisite for ... their flanking regions revealed high variation, which may be characteristic for polyploids with a ... microsatellite flanking-sequences was a prerequisite for the development of co-dominant markers for fragment ...
MDC1: The art of keeping things in focus - Zurich Open Repository a...
... flanking sites of DNA double-strand breaks. The assembly of these structures-usually termed DNA damage foci ... chromatin domains flanking sites of DNA double-strand breaks. The assembly of these structures-usually ... damage. Many DNA damage response proteins accumulate in large chromatin domains flanking sites of DNA ... flanking sites of DNA double-strand breaks. The assembly of these structures-usually termed DNA damage foci ...
Microsoft Word - Nuvolone JBC Letter 20150831 sumbission revised.docx
... . Consequently, the genomic region of B10.129‐PrnpEdbg/Edbg mice flanking the targeted Prnp locus contains ... ). This phenomenon, intrinsic to all congenic knockout mice, is known as the flanking gene problem ... . Consequently, the genomic region of B10.129‐PrnpEdbg/Edbg mice flanking the targeted Prnp locus contains ... ). This phenomenon, intrinsic to all congenic knockout mice, is known as the flanking gene problem ...
Metal ions and sugar puckering balance single-molecule kinetic hete...
... long-range tertiary interactions between the intron and its flanking exons. By single-molecule FRET, we ... interactions between the intron and its flanking exons. By single-molecule FRET, we explore the binding ... tertiary interactions between the intron and its flanking exons. By single-molecule FRET, we explore the ... intron and its flanking exons. By single-molecule FRET, we explore the binding kinetics of the most ...
Generation and functional characterization of mice with a condition...
... , we generated mice in which the Bmp7 gene has been rendered conditional-null by flanking its first ... , we generated mice in which the Bmp7 gene has been rendered conditional-null by flanking its first ... flanking its first coding exon with loxP sites. To this end, we adapted the two-loxP site strategy to ... conditional-null by flanking its first coding exon with loxP sites. To this end, we adapted the two-loxP site ...
Coupling of remote alternating-access transport mechanisms for prot...
... flanking α-helices that project from the membrane. Moreover, we rationalize how the cross-talk among ... two distinct types of collective motions of two structural repeats, coupled by flanking α-helices that ... two distinct types of collective motions of two structural repeats, coupled by flanking α-helices that ... motions of two structural repeats, coupled by flanking α-helices that project from the membrane. Moreover ...
Different base/base mispairs are corrected with different efficienc...
... , respectively, and repair bias was influenced by mismatch flanking sequences. Abstract Mismatches arise during ... repair bias was influenced by mismatch flanking sequences. 180 citations in Scopus® 0 downloads since 12 ... % efficiencies, respectively, and repair bias was influenced by mismatch flanking sequences. Abstract Mismatches ... , respectively, and repair bias was influenced by mismatch flanking sequences. Find similar titles Statistics ...
